NOT KNOWN FACTUAL STATEMENTS ABOUT THR777

Not known Factual Statements About thr777

Not known Factual Statements About thr777

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ClinVar contains an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice site are a comparatively popular explanation for aberrant splicing (PMID: 17576681, 9536098). Algorithms formulated to forecast the influence of sequence alterations on RNA splicing recommend this variant could produce or strengthen a splice web page. In summary, the readily available evidence is currently inadequate to find out the role of this variant in condition. Hence, it's been categorised like a Variant of Uncertain Importance. (significantly less)

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This day signifies the final time this VCV record was updated. The update may be because of an update to one of many involved submitted documents (SCVs), or because of an update that ClinVar created on the variant for instance introducing HGVS expressions or a rs quantity.

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This price is calculated by NCBI based on info from submitters. Read through our regulations for calculating the evaluate position. The number of submissions which contribute to this evaluation status is revealed in parentheses.

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The submitting organization for this submitted (SCV) history. This column also features the SCV accession and Model variety, the day this SCV 1st appeared in ClinVar, as well as the date this SCV was final current in ClinVar.

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The worldwide minimal allele frequency calculated via the a thousand Genomes Venture. The slight allele at this locale is indicated in parentheses and may be distinct with the allele represented by this VCV history.

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